ECST
(1998)Objective
To evaluate the benefit of CEA in patients with symptomatic carotid artery stenosis.
Study Summary
• CEA was effective in reducing the risk of stroke in patients with symptomatic stenosis >80%..
Intervention
Carotid endarterectomy (CEA) versus medical management.
Inclusion Criteria
3000 patients with any degree of stenosis who were symptomatic within the past 6 months.
Study Design
Arms: CEA vs. Medical Management
Patients per Arm: 3000 patients (split between CEA and medical management)
Outcome
• Risk of major stroke or death complicating surgery was high at 7%. <br>• The 3-year stroke risk was 14.9% in the CEA group vs.26.5% in the control group..