All Clinical Trials

ACAS 1995 ACCORD 2008 ACST 2004 ACTIVE A 2009 ACTIVE W 2008 ADAPT AF-DES 2025 AFIRE 2019 ALISAH 2012 ALONE-AF 2025 ALPACA 2025 AMASCIS 2022 AMPLITUDE-O 2021 ANGEL-ASPECT 2023 ANGEL-ASPECT Post-Hoc (CTP Mismatch) 2024 ANGEL-COAST 2025 ANGEL-REBOOT 1-year 2025 ANGEL-TNK 2025 ANNEXA-I 2024 APACHE-AF 2021 AQUATIC 2025 ARAIS 2023 ARAMIS 2023 ARAMIS Post hoc (LVO) 2024 ARCADIA 2024 ARCADIA-MRI 2025 ARCH 2014 ARISTOTLE 2011 ARPEGGIO 2025 ARRIVE 2018 ARTESIA 2024 ASCEND 2018 ASPREE 2018 ASSERT 2012 ASSET-IT 2025 ASTER 2017 ASTRO-APS 2022 ATACH-2 2016 ATAMIS 2024 ATAMIS Post Hoc LAA 2024 ATIS-NVAF 2025 ATLAS 2020 ATTENTION LATE 2025 ATTENTION-IA 2025 ATTICUS 2023 AUGUSTUS 2019 AVERROES 2011 AVERT 2015 AXIOMATIC-SSP 2024 AZALEA–TIMI 71 2025 Amulet IDE 2021 Atrial Pouch 2025 BABY HUG 2012 BAOCHE 2022 BASICS 2021 BASIS 2024 BAST 2023 BEST-II 2023 BEST-MSU 2021 BHF PROTECT-TAVI 2025 BP-TARGET 2022 BP-TARGET AHT Substudy 2022 BPROAD 2025 BRAT 2011 BRETIS-TNK 2024 BRIDGE-TNK 2025 CABANA 2019 CADISS 2019 CAISR 2022 CAPRIE 1996 CAPTIVA 2023 CARS 2016 CARS 2016 CASONI 2025 CASSISS 2022 CATALYST 2025 CATCH-AF Score 2026 CATHARSIS 2015 CATIS-ICAD Phase III CATIS-ICAD Pilot 2015 CEREHETIS 2023 CERES-TANDEM 2026 CERUS 2022 CHABLIS-T II 2025 CHAMPION-AF 2026 CHANCE 2013 CHANCE-2 2021 CHANCE-3 2024 CHANCE-4 2025 CHARM 2024 CHOICE 2022 CHOICE2 2026 CIAN 2022 CICAS 2014 CLAIR 2010 CLARYS 2022 CLEAR Colchicine 2025 CLEAR Eptifibatide 2008 CLEAR III 2017 CLEAR LVO 2022 CLOSE 2017 CLOSURE I 2012 CLOSURE-AF 2026 CLOTBUST 2004 CLOTBUST-ER 2019 CMOSS 2023 COBRIT 2009 COCROACH 2023 COMMANDER HF 2018 COMMIT 2025 COMPASS 2020 CONSCIOUS-1 2008 CONSCIOUS-2 2011 CONSCIOUS-3 2012 CONVINCE 2024 CORALreef Lipids 2026 COSS 2011 CRAO AGILE Metanalysis 2025 CREST 2010 CREST-2 2025 CRYSTAL AF 2014 CSPS 2019 CYTO-PV 2013 CaCTUSES 2022 Caravaggio 2020 Cardiac CT in LVO Stroke 2025 Cardiac CT vs TTE 2022 DATE 2025 DAWN 2018 DAYLIGHT 2025 DECOMPRESS-2 2024 DEFENSE-PFO 2018 DEFUSE 3 2018 DESTINY 2007 DEVT 2021 DIAS 2005 DIRECT-MT 2020 DIRECT-SAFE 2022 DISCOUNT 2024 DISTAL 2025 DISTALS 2025 DO-IT 2025 DO-IT Target Analysis 2025 DOAC LVAD 2025 DOAC-CVT 2025 DOAC-IVT 2023 DUSK 2024 Dantrolene SAH Trial 2014 Dapsone In SAH 2022 EAGLE 2010 EARLYDRAIN 2023 EBBINGHAUS PCSK9 2017 ECASS I 1995 ECASS I Post Hoc 1998 ECASS II 1998 ECASS III 2008 ECLAP 2004 ECST 1998 ECST-2 2025 EDEN 2023 EDESTROKE 2026 EFFECTS 2021 EINSTEIN Jr 2019 ELAN 2023 EMBOLISE 2024 EMBOLISE 2 2026 EMBRACE 2014 EMMA-CAN 2025 EMPHASIS 2026 EMPROTECT 2025 ENCHANTED (BP after IVT) 2023 ENCHANTED (Swelling Analysis) 2025 ENCHANTED (low dose tPA) 2016 ENCLOSE 2023 ENGAGE AF-TIMI 48 2013 ENRICH 2024 EPIC-CAD 2024 ERSIAS Trial 2020 ESCAPE 2015 ESCAPE-MeVO 2025 ESCAS Cerebrolysin 2025 ESPRIT - Intensive Blood Pressure Control on Stroke 2025 ESPS2 1996 ETERNAL-LVO 2025 ETIS-TETRIS 2026 EVT vs BMT Low NIHSS Metanalysis 2023 EWOLUTION 2017 EXPECTS 2025 EXSCEL 2017 EXTEND 2019 EXTEND-IA 2015 EXTEND-IA TNK 2018 EXTEND-IA TNK Part 2 2020 Efficacy of tPA in CRAO 2011 Emergent Stenting After IVT 2019 ExStroke 2009 Ez-PAVE 2026 FASTEST 2026 FOCUS 2023 FOURIER 2017 FRED 2021 GASH 2019 GASS 2022 GORE-REDUCE 2017 GSR Tandem Lesions 2021 GiACTA 2017 GiACTA Longterm 2021 Goal-Directed Hemodynamic Therapy After SAH 2020 HAMLET 3-year 2013 HDS-SAH 2015 HINTS 2009 HOPE 2025 HOPE-2 2006 HOPE-3 2016 HOPE-3 (Stroke Analysis) 2021 Hokusai VTE Cancer 2018 IAT-TOP 2025 ICSS 2015 ICTUS 2012 IHAST 2005 IMASH 2010 IMPROVE-IT 2015 INSIST-HRMRI INSPIRES 2023 INTERACT (Pilot) 2008 INTERACT2 2013 INTERACT3 2023 INTERACT4 2024 INTERSTROKE 2024 IRIS 2025 ISAT 2005 ISCVT 2004 ISPASM 2021 IST-3 2012 IVT for Minor Stroke 2024 Ipsilesional Arm Remediation 2026 JAM 2014 JELIS 2007 JPPP 2014 KIDS-DOTT 2022 LAACS 2022 LAACS with cardiac surgery 2018 LAAOS III 2021 LAIS 2026 LASTE 2024 LEADER 2016 LOOP 2021 MAGIC-MT 2024 MASH 2006 MASH-2 2012 MERCI 2005 MIND 2025 MISTIE III 2019 MOST 2024 MR CLEAN 2015 MR CLEAN-NO IV 2021 MR RESCUE 2013 MR WITNESS 2018 Microbubble 2016 Multi MERCI 2008 NASCET 1991 NAVIGATE ESUS 2018 NAVIGATE ESUS LV Dysfunction Subgroup 2021 NICARDIPINE Implant 2024 NINDS 1995 NOAH-AFNET 6 2023 NOR-TEST 2017 NicaPlant 2023 OAC-ALONE 2019 OCEAN 2025 OCEANIC-AF 2025 OCEANIC-STROKE 2026 ODYSSEY OUTCOMES 2018 OPTIMAL-BP 2023 OPTIMAS 2024 OPTIMIST 2020 OPTIMISTmain 2025 OPTION 2026 OPTION LAAC 2025 ORIENTAL MEVO 2025 PACIFIC-Stroke 2022 PAST-BP 2016 PATCH 2016 PAUSE TAVI 2025 PEARL 2025 PER DIEM 2021 PHADER 2020 PHAST-TRAC 2018 PILLAR 2019 PILLAR-XT 2025 PINNACLE FLX 2023 PIONEER 6 2019 PLATO 2023 POINT 2018 POST-TNK 2025 PRAGUE-17 2020 PRECISION 2016 PREDIMED 2018 PREMIER 2023 PRERISK 2024 PRESTIGE-AF 2025 PREVAIL 2014 PRIORITY-CVT 2020 PRISMS 2018 PROACT 1998 PROLEVIS 2025 PROST-2 2025 PROTECT AF 2014 PRoFESS 2008 PT1 2005 Penumbra 2009 Penumbra Separator 3D 2017 Prostacyclin in SAH 2015 RACECAT 2022 RAISE 2024 RAPS 2016 RAVE 2010 RE-ALIGN 2013 RE-LY 2009 RE-SPECT CVT 2019 RE-SPECT ESUS 2019 REACT 2025 REDUCE-IT 2019 RESCUE BT2 2023 RESCUE Phase II 2025 RESCUE-Japan LIMIT 2022 RESCUE-RESS 2025 RESPECT 2017 RESTART 2019 REVASCAT 2015 REWIND 2019 RITUXVAS 2010 ROADSTER 2015 ROADSTER 2 2022 ROADSTER 2 Early Outcomes 2020 ROADSTER 3 2024 ROCKET AF 2011 ROSE-TNK 2023 ReHAND-BCI 2025 Rivaroxaban for Cognitive Decline Prevention in Low-Risk Atrial Fibrillation 2026 SAHARA 2025 SAHRANG 2025 SALUTE 2018 SAMMPRIS 2011 SAPPHIRE 2008 SAS 2024 SCS for Post-Stroke Hemiparesis 2025 SECURIS 2025 SELECT 2023 SELECT Late 2023 SELECT-D 2018 SELECT2 2023 SELECT2 1-Year 2024 SIT 2014 SKIP 2021 SOCRATES 2016 SOLO-ESUS 2025 SONIC 2022 SOUL 2025 SPACE 2008 SPAF 1991 SPAN (Tocilizumab) 2025 SPARCL 2006 SPRINT 2021 SPS3 2012 SPS3 Blood Pressure 2013 STABLED 2026 START 2025 STEM 2024 STEPS 2016 STICH II 2013 STITCH 2015 STOP 1998 STOP II 2005 STOP-AUST 2020 STOP-CAD 2024 STOP-CAD tPA 2024 STOP-MSU 2024 STRATIS Tandem Lesion 2019 STROKE-AF 2021 STROKE-AF 3-Year 2023 SURMOUNT-OSA 2024 SURPASS-CVOT 2025 SUSTAIN-6 2016 SWIFT DIRECT 2021 SWIFT PRIME 2015 SWISS-APERO 2022 SWITCH 2024 SWITCH Location Analysis 2025 Scope Meta-Analysis (PFO PASCAL Outcomes) 2026 SoSTART 2021 Spectral Cardiac CT in Acute Stroke 2023 T-FLAVOR 2025 TAKT 2018 TAKT Longterm 2020 TARDIS 2018 TASTE 2019 TASTE-2 2026 TEACH 2018 TEMPO-2 2024 TESLA 2023 THALES 2020 THAWS 2020 THAWS2 2024 THEIA 2025 THERAPY 2016 TICH-2 2018 TIMELESS 2024 TIMING 2022 TITAN 2016 TNK 4.5-24h Meta-Analysis 2025 TO-ACT 2020 TOAST 1993 TOSS-2 2011 TRACE-5 2026 TRACEIII 2024 TRAPS 2018 TRAPS 2 Years Outcomes 2021 TRAVERSE 2023 TREAT-CAD 2021 TREAT-CAD 6-months 2025 TREND 2023 TRIDENT 2025 TRIUMPH 2015 TRIVASOSTIM 2023 TST 2020 TWIST 2023 TWiTCH 2016 TenCRAOS 2026 Tiopronin Trial 2010 UKPDS 1998 ULTRA 2020 VANQUISH 2024 VAST 2015 VENOST 2017 VISP 2005 VISSIT 2015 VIST 2019 VITATOPS 2010 VNS-REHAB 2021 VNS-REHAB 1-Year Outcomes 2025 Venous-TD 2025 WAKE-UP 2018 WARCEF 2012 WARSS 2001 WASID 2005 WEAVE 2019 WHS Biomarkers 2024 ZODIAC 2025 aMAZE 2024 ta-VNS for acute stroke 2022

ACHIEVE I & II 2020 ADVANCE 2021 APPRAISE 2024 ARISE 2018 Acupuncture for Episodic Migraine 2020 Acupuncture for Migraine Prophylaxis 2017 CGRP-CV 2026 CHAMP 2017 COURAGE 2024 DHE IV for Intractable Migraine 1986 EVOLVE-1 2018 EVOLVE-2 2018 Fremanezumab for Episodic Migraine 2018 Frovatriptan for Menstrual Migraine MAM 2004 GALiC 2019 HALO CM 2017 HALO EM 2018 HER-MES 2022 High Flow Oxygen for Cluster 2009 IIHTT 2014 Intranasal Zolmitriptan in Acute Cluster Headache 2006 Lasmiditan for acute migraine 2019 MOH Treatment Strategies 2020 MOTS 2022 PREEMPT 2 2010 PREEMPT I 2010 PREMICE 2013 PROMISE-2 2020 REGAIN 2018 REN for Migraine 2023 SAMURAI and SPARTAN Pooled Analysis 2019 SPACE 2026 STRIVE 2017 TEAM 2022 Ubrogepant for Acute Migraine 2019 ZOTRIP (Post-Hoc) 2018 Zavegepant Intranasal 2023 Zolmitriptan 042 Trial 1997 Zolmitriptan Intracutaneous for Acute Migraine 2021 Zolmitriptan for Menstrually Associated Migraine 2004

Alldredge SE 2001 Cannabidiol as Adjunct for LGS 2018 Cannabidiol in Dravet Syndrome 2017 Cenobamate C013 2021 Cenobamate C017 2022 Chamberlain SE 2014 Colbazam, Adjunct for LGS 2015 ERSET (Early Surgery for MTLE) 2012 ESETT 2020 EXIST-3 2016 Eslicarbazepine Antiepileptogenesis 2026 FREEDOM 2025 Fenfluramine Dravet Study 2019 GWPCARE1 2017 GWPCARE3 2018 KOMET 2013 LTG vs CBZ 1995 Lacosamide (Adjunct for Partial) 2010 Lacosamide as Adjunct for Generalized Seizures 2015 Lacosamide for Focal Seizures 2019 Levetiracetam as Adjunct for Partial 2000 MESS 2005 MONARCH/ADMIRAL (Zorevunersen in Dravet Syndrome) 2026 North American AED Pregnancy Registry 2025 RAMPART 2012 RNS Pivotal Trial 2011 RNS System Pivotal Trial 2011 SANAD I 2007 SANAD II 2021 SANTE (DBS for Refractory Focal) 2010 STICLO 2000 Treiman SE 1998 VA Cooperative Study 1985 VALOR 2020 VNS Study 1995 VNS for Partial Seizures 1998 Wiebe 2001 2001 Wiebe Surgery for TLE 2001 X-TOLE 2023

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor 2016 ADAGIO 2009 AIM-TD 2017 ARM-TD 2017 AZA-PD 2025 BIPARK-2 2017 Bilateral FUS ET 2024 CALM-PD 2000 CALM-PD Long-term 2009 CSP 468 2010 DATATOP 1989 DBS Dystonia 2006 DBS-PD 2006 EARLYSTIM 2013 ELEVATE-PD 2025 ELLDOPA 2004 EXPRESS 2004 Exenatide-PD3 2025 FIRST-HD 2016 FUS ET 2016 FUS PD 2017 Focused Ultrasound Subthalamotomy for Parkinson Disease 2020 GENERATION HD1 2023 German PD Study Group DBS Trial 2006 KINECT 3 2017 KINECT 4 2019 KINECT-HD 2023 LARGO 2005 LEAP 2019 LIXIPARK 2024 MRgFUS Thalamotomy for ET 2016 NSTAPS 3-Year 2016 OPTIMO 2026 PADOVA 2025 PASADENA 2022 PD MED 2022 PD SURG 2010 PRIDE-HD 2020 SETTLE 2017 SP512 Rotigotine 2007 SPARK 2022 SPIDY 2005 SPIDY 3-Year 2007 STARDYS 2018 TEMPO 2002 TEMPO-3 2026 TETRA-HD 2009 Trial of Pimavanserin in Dementia-Related Psychosis (HARMONY) 2021

A4 2023 AHEAD 3–45 APOLLOE4 2025 Bapineuzumab 2014 CATIE-AD 2006 Clarity AD 2023 DIAN-TU 2025 DOMINO-AD 2012 EBBINGHAUS 2017 ELEVATE-PD 2025 EMERGE / ENGAGE 2022 EVOKE/EVOKE+ EXPEDITION3 2018 FUS-Aducanumab 2024 GATE 2015 GRADUATE I & II 2023 HARMONY 2021 Hydromethylthionine Mesylate (HMTM) for MCI and Mild-to-Moderate Alzheimer Disease 2026 MEM-MD-02 2003 MIND Diet Trial 2015 Plasma p-tau217 Clock 2026 Plasma p-tau217 Clocks for Predicting Onset of Alzheimer Disease 2026 Plasma p-tau217 Lumipulse Assay for Alzheimer Disease Diagnosis 2025 Plasma p-tau217 Validation 2025 Plasma p-tau217 as a Clinical Trial Endpoint for Alzheimer Disease 2026 RT-QuIC Nasal Brushing 2014 TRAILBLAZER-ALZ 2021 TRAILBLAZER-ALZ 2 2023 Verubecestat-Prodromal 2019

ACT DMD 2017 ADAPT 2021 ADAPT+ 2024 ALS/Riluzole Study 1994 Arimoclomol in IBM 2023 BCMA-Targeted CAR-T Cell Therapy for Generalized Myasthenia Gravis 2026 BeatMG 2022 CENTAUR 2020 CHAMPION MG OLE 2023 CHERISH 2017 CIFFREO 2026 DAP for LEMS 2000 DELOS 2015 DEVOTE 2026 Deflazacort in DMD 2016 Descartes-08 2026 Dutch GBS Trial 1992 EMBARK 2026 ENDEAR 2017 EPIDYS 2024 Edaravone ALS 19 Study 2017 FIREFISH 2021 HEALEY ALS Platform Trial 2025 HELIOS-A 2021 High-Dose Nusinersen for Spinal Muscular Atrophy 2026 ICE 2008 IGIV-C MG Exacerbation Study 2019 IV Edaravone ALS Survival Study 2022 LUMINESCE 2025 Léger MMN IVIg 2001 MARINA (Delpacibart Etedesiran for Myotonic Dystrophy Type 1) 2026 MGTX 2016 MINT 2025 Methotrexate in MG 2016 MycarinG 2023 NEURO-TTR 2018 NEURO-TTRansact 2023 NURTURE 2019 Nuedexta Bulbar Function Trial 2017 Osterman PE for GBS 1982 PARADIGM 2026 PLEO-CMT 2021 PRIMA 2013 PROPEL 2021 Prednisone in Duchenne Dystrophy (Griggs) 1991 ProDERM 2022 QALS 2009 REGAIN 2017 RESCUE-ALS 2023 RINOMAX 2022 RNS60-ALS 2023 Riluzole Dose-Ranging Study 1996 SAPPHIRE SID-GBS 2021 START (Zolgensma Phase 1) 2017 STR1VE 2021 Tocilizumab ALS Safety Trial 2021 ULTIMATE I & II 2022 VALOR 2022 Viltolarsen Phase 2 in DMD 2020 Weekend vs Daily Prednisone in DMD 2011

AVAglio 2014 Abemaciclib for Recurrent Meningiomas with NF2 or CDK Pathway Alterations 2026 CSF WGS (Liquid Biopsy) for Pediatric Tumors 2024 FDOPA-PBT-Glioblastoma 2024 INCIPIENT 2024 INDIGO 2023 Liquid Biopsy for CNS Lymphoma 2021 Liquid Biopsy for Glioma 2023 MGMT Methylation Study (Hegi et al.) 2005 Oncolytic Virus for Recurrent Glioblastoma — Spatial Omics Analysis 2026 Perry (NCIC CE.6/EORTC 26062) 2017 RTOG 0825 2014 RTOG 9802 2016 Rapid CSF DNA Analysis 2024 SRS vs HA-WBRT for Brain Metastases 2026 Stupp Protocol (EORTC 26981/NCIC CE.3) 2005

AFFIRM 2006 ASCEND 2018 ASCLEPIOS I & II 2020 BENEFIT 15-Years 2024 CARE-MS I 5-Year 2017 CHAMPION-NMOSD 2023 CHAMPS 2000 CLARIFY-MS 2023 CLARITY Extension 2018 CLASSIC-MS (CLARITY/CLARITY Extension Cohort) 2023 CONFIRM 2012 CombiRx 2013 Comparative Efficacy of DMT in NMOSD 2026 Copolymer 1 1995 Copolymer-1 Pivotal Trial 1995 D-Lay MS 2025 DEFINE 2012 Dalfampridine 2016 Dalfampridine Longterm 2015 Duloxetine for Central Pain in MS 2015 EARLIMS 2020 EXPAND 2018 Eculizumab NMO Pilot 2013 Estriol-RRMS 2016 FREEDOMS 2010 GEMINI 1 and GEMINI 2 2025 HERCULES 2025 IFNB MS Study 1993 LEARN 2025 MAGNIFY-MS 2022 MAINRITSAN 2014 MS-STAT 2014 N-MOmentum 2019 ONTT 1992 OPERA 9-Year 2025 OPERA I & II 2016 ORACLE MS 2014 ORATORIO 2016 Ocrelizumab Phase 2 2011 PREVENT 2019 PRISMS 1998 PRISMS-4 2001 PreCISe 2009 REFLEX 2014 RIN-1 2020 ReBUILD 2017 SAkuraMoon 2025 SAkuraSky 2019 SAkuraStar 2020 SENTINEL 2006 SPI2 2020 TEMSO 2011 TERIS 2023 TOWER 2014 TRANSFORMS 2010 Treatment Discontinuation in MOGAD 2026 ULTIMATE I and II 2022